Menopause brings a wave of physical and emotional changes, but finding relief shouldn’t feel overwhelming. We’ve created Harmonia to support women through this transition with a science-backed solution to help ease hot flashes, night sweats, mood swings, sleep disturbances, and other bothersome symptoms.
This article explains what causes menopausal symptoms, and how Harmonia works to provide natural, hormone-free relief, so women can feel empowered to embrace this new chapter with confidence and comfort.
Why Do Menopausal Symptoms Happen?
Menopause is when menstrual cycles stop, marking the end of fertility and menstrual periods.
Throughout a woman’s reproductive years, the two hormones that drive the menstrual cycle-–estrogen and progesterone—rise and fall in a typical, monthly rhythm. After decades of this cycle, the body becomes accustomed to these hormones as a foundation for equilibrium.
When the menopause transition begins, this cycle gradually slows during a period known as perimenopause, before eventually stopping. As a result, the body’s production of estrogen and progesterone decreases significantly. Estrogen and progesterone receptors are located throughout the body, and they can be quite sensitive to the sudden absence of these hormones, disrupting the body’s sense of balance.
This hormonal decline triggers a wide range of physical, emotional, and cognitive symptoms as tissues with hormone receptors struggle to adapt. For example, the hypothalamus—an area of the brain that regulates body temperature—is sensitive to estrogen’s absence, causing hot flashes and night sweats. Estrogen also affects neurotransmitters that regulate mood like serotonin and dopamine, leading to menopausal mood swings and irritability.
Hot flashes, night sweats, and mood changes are among the most common symptoms of menopause, but many are possible, including sleep disturbances, fatigue, vaginal dryness, joint pain, weight gain, memory issues, hair thinning, and changes in libido.
What is Harmonia?
Harmonia is a daily, hormone-free dietary supplement carefully formulated with natural, patented bioactive ingredients. Harmonia is designed for multi-symptom relief, directly targeting menopausal symptoms like hot flashes, night sweats, sleeplessness, mood swings, stress, and vaginal discomfort.
How does Harmonia Work to Ease Symptoms of Menopause?=
While many forms of menopause relief involve replacing the hormones that are naturally declining during this life stage, Harmonia is completely hormone-free, meaning it does not contain any hormones, hormone-like compounds, or other substances meant to mimic the effect of hormones in the body.
Instead, Harmonia’s clinically proven, patented ingredients use botanical mechanisms to target the source of the symptom itself. Here’s what’s inside:
EstroG-100®
EstroG-100 is a standardized extract of three herbs long used in Traditional Chinese and Korean medicine: Cynanchum wilfordii (Silk plant), Phlomis umbrosa (Fireweed), and Angelica gigas (Red angelica). Clinical studies have shown that EstroG-100 helps alleviate menopausal symptoms and improve quality of life without causing adverse effects or altering estrogen or other hormone levels (1-4). Additionally, EstroG-100 has demonstrated benefits for bone health, a key concern for women during menopause (4).
SaffSerene™
SaffSerene is a standardized extract of saffron (Crocus sativus L.), renowned as the world’s most expensive spice. Its key bioactive compounds—safranal, crocin, and picrocrocin—support mood balance, mental well-being, and stress response, making it beneficial for managing menopausal symptoms (5-7).
Probiotics
Harmonia also features two of the world’s most scientifically studied probiotic strains: Lactobacillus rhamnosus GR-1® and Lactobacillus reuteri RC-14®, which support vaginal health by promoting beneficial bacteria, inhibiting harmful bacteria, and maintaining optimal pH (8-10). These probiotics have been featured in over 100 scientific publications.
Real Results
While Harmonia’s ingredients are backed by strong clinical evidence, we conducted an internal study to evaluate the effectiveness of the complete formula. In a 90-day trial with 15 menopausal women using Harmonia—without hormone therapy or major lifestyle changes—participants reported significant symptom relief:
● 93% experienced fewer hot flashes and night sweats
● 87% noticed improved sleep quality
● 86% felt better equipped to manage stress
● 83% experienced improved mood and reduced irritability
● 71% reported enhanced sexual health
Individual results may vary, but this study underscores Harmonia’s potential to provide comprehensive, hormone-free menopause relief.
Find Your Balance with Harmonia
Menopause may bring challenges, but with Harmonia, relief is within reach. Using only natural, clinically proven ingredients, Harmonia offers a safe, hormone-free way to ease symptoms and enhance well-being. Embrace this new chapter with confidence, comfort, and grace—because every woman deserves to feel her best at every stage of life.
References
1. Chang A, Kwak BY, Yi K, Kim JS. The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study. Phytother Res. 2012 Apr;26(4):510-6. doi: 10.1002/ptr.3597. https://pubmed.ncbi.nlm.nih.gov/21887807/
2. Kirubamani H, Ahire P, Stalin C. Evaluation of Efficacy and Safety of EstroG-100® in Alleviating Menopausal Symptoms in Postmenopausal Women in India: A Prospective, Single-center, Single-arm, Interventional Study. J Midlife Health. 2023 Oct-Dec;14(4):285-290. doi: 10.4103/jmh.jmh_220_23. https://pubmed.ncbi.nlm.nih.gov/38504729/
3. Farzaneh F, Fallah G, Khalili-Chelik A, Fallah A, Hosseini M. Estro G-100 herbal extract and hot flashes in postmenopausal women: A randomized double-blinded controlled trial. Explore (NY). 2024 May-Jun;20(3):334-339. doi: 10.1016/j.explore.2023.09.004. https://pubmed.ncbi.nlm.nih.gov/37778911/
4. Tak K, Ryu K-J, Lee S, Lee D-J, Seo S-K. A 12-Week, Multi-Center, Double-Blind, Randomized, Placebo-Controlled Clinical Trial for the Evaluation of the Efficacy and Safety of the Herbal Extract (EstroG-100®) on Menopausal Symptoms. J Reprod Med Gynecol Obstet 2022, 7: 106. DOI: 10.24966/RMGO-2574/100106.
5. Hasheminasab FS, Azimi M, Raeiszadeh M. Therapeutic effects of saffron (Crocus sativus L) on female reproductive system disorders: A systematic review. Phytother Res. 2024 Jun;38(6):2832-2846. doi: 10.1002/ptr.8186. https://pubmed.ncbi.nlm.nih.gov/38558480/
6. Delam H, Keshtkaran Z, Shokrpour N, Eidi A, Bazrafshan MR. The effect of Crocus sativus L. (saffron) herbal tea on happiness in postmenopausal women: a randomized controlled trial. BMC Complement Med Ther. 2023 Jun 1;23(1):176. doi: 10.1186/s12906-023-04014-8. https://pubmed.ncbi.nlm.nih.gov/37264347/
7. Agha-Hosseini M, Kashani L, Aleyaseen A, Ghoreishi A, Rahmanpour H, Zarrinara AR, Akhondzadeh S. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. BJOG. 2008 Mar;115(4):515-9. doi: 10.1111/j.1471-0528.2007.01652.x. https://pubmed.ncbi.nlm.nih.gov/18271889/
8. Reid G, Charbonneau D, Erb J, Kochanowski B, Beuerman D, Poehner R, Bruce AW. Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women. FEMS Immunol Med Microbiol. 2003 Mar 20;35(2):131-4. doi: 10.1016/S0928-8244(02)00465-0. https://pubmed.ncbi.nlm.nih.gov/12628548/
9. Ho M, Chang YY, Chang WC, Lin HC, Wang MH, Lin WC, Chiu TH. Oral Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 to reduce Group B Streptococcus colonization in pregnant women: A randomized controlled trial. Taiwan J Obstet Gynecol. 2016 Aug;55(4):515-8. doi: 10.1016/j.tjog.2016.06.003. https://pubmed.ncbi.nlm.nih.gov/27590374/
10. Petrova MI, Lievens E, Verhoeven TL, Macklaim JM, Gloor G, Schols D, Vanderleyden J, Reid G, Lebeer S. The lectin-like protein 1 in Lactobacillus rhamnosus GR-1 mediates tissue-specific adherence to vaginal epithelium and inhibits urogenital pathogens. Sci Rep. 2016 Nov 21;6:37437. doi: 10.1038/srep37437. https://pmc.ncbi.nlm.nih.gov/articles/PMC5116675/
